Today, the role of regional organizations such as BRICS in reducing the consequences of the dollar and de-dollarization on the global economy is one of the key issues in the global economy. From this perspective, BRICS, as a club of emerging economies, has special capacities such as economic diversification, natural resources, and large domestic consumption markets to reduce the role of the dollar. Evidence suggests that BRICS members have established independent financial mechanisms such as the New Development Bank and alternative payment systems and have taken steps to strengthen economic cooperation among members and develop strategic partnerships, which can help reduce costs and regulate new mechanisms in this regard. However, this process faces challenges such as domestic political and economic differences among BRICS members, resistance from Western economies, and the complexities of coordinated and common policies. Accordingly, the main question of this research is how BRICS can reduce dependence on the dollar and what opportunities and bottlenecks exist in this regard? In response to this hypothesis, it is proposed that BRICS can reduce the role of the dollar in the global economy by strengthening economic diversification, creating new trade mechanisms, and strategic partnerships. This research aims to identify economic strategies, opportunities, and bottlenecks in the path of dedollarization and attempts to evaluate this issue in relation to a global order. The results of the research indicate that dedollarization has led to strengthening economic independence and reducing economic and political dominance at the global level, and this change in the global economic order paves the way for more sustainable development of BRICS members. This research, using dependency theory and a qualitative method and an analytical-descriptive approach, has analyzed economic structures and unequal relations between the center and the periphery.